The Race Across America (RAAM) - the "World's Toughest Race" - is a 3,000 miles bicycle race that starts in Oceanside, CA and ends in Annapolis, MD. In 2016, I was very fortunate to work for 3000 to a Cure and document one of their cyclists, Marshall Reeves, as he tried to complete RAAM while raising money for brain cancer research.
Marshall summed it up perfectly in his post-race interview: "It is pretty selfish if all you're doing is [racing]. It's a lot of pain, a lot of training, a lot of sacrifice, but it's something you volunteer for. Whereas people who are afflicted by a lot of diseases, in particular brain cancer, they didn't pick that battle but they're faced with it and it's just as daunting and devastating as it can be. Far more so than this race. You can stop racing, you can finish the race ... but if you are diagnosed with brain cancer, it's a death sentence. And so I realized I needed to do something worthwhile with this effort or it would just be for naught."
Marshall completed the race in 12 days, 13 hours, and 52 minutes and raised over $16,000 dollars for brain cancer research.